Would you like to learn how to use the brand-new IMPRES-M methodology to estimate PK models “without the model”? Come join us for this half-day workshop where you will learn about the theory behind the impulse-response framework, and where you will get hands-on experience on how to use it.

Date and time
Tuesday 3rd of June, 13:00-17:00

Venue
Megaron, Thessaloniki Concert Hall (Main venue) – Room CR-3

Instructors
Workshop host: Jeroen Elassaiss-Schaap
Workshop tutors: Vincenzo d’Iorio, and Lorenzo Cifelli

Workshop description
Population PK modeling is a major interest among the PAGE community. With IMPRES-M, we have proudly established a new approach to describing pharmacokinetic (PK) and pharmacodynamic (PD) curves by smoothing rather than modeling, such as compartmental or differential-equation based modeling. This is achieved in a framework that allows simulation and extrapolation, similar to what is available in compartmental models. You therefore can be more efficient in your modeling workflows!
In this workshop you will be presented by the background and theory, but you will also get your hands on fitting data with IMPRES-M, either your own or datasets provided by us. We focus on its application to single-subject PK curves. Furthermore we will present briefly about further capabilities, and extensions that are under development so you will also get to know where we will be heading next!

Learning objectives:
• IMPRES-M theory for PK modeling
• Hands-on single-subject PK modeling with IMPRES-M
• Further IMPRES-M capabilities
• Ongoing research on IMPRES-M extensions

Target Audience
The target audience are PK or PK-PD modelers at beginner to advanced levels, who would like to extend their modeling toolkit.

Prerequisites
Attendees need to bring their own laptop with a recent version of R and Rstudio installed. Instructions to install IMPRES-M as an R package will be provided beforehand.